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Extracellular Matrix and The Liver Approach to Gene Therapy

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Published by Academic Press .
Written in English


Book details:

Edition Notes

ContributionsIsao Okazaki (Editor), Yosifumi Ninomiya (Editor), Tanikawa Kyuichi (Editor), Scott I. Friedman (Editor)
The Physical Object
Number of Pages512
ID Numbers
Open LibraryOL7328412M
ISBN 10012525251X
ISBN 109780125252515

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Extracellular Matrix and the Liver is an overview of recent progress in understanding the cellular and molecular basis of liver fibrosis, with a review of prospective targets for therapy. Cirrhosis of the liver has been believed to be progressive and incurable. However, interferon therapy for HCV-positive chronic hepatitis and/or liver cirrhosis shows dramatic recovery in some cturer: Academic Press. Extracellular Matrix and the Liver is an overview of recent progress in understanding the cellular and molecular basis of liver fibrosis, with a review of prospective targets for therapy. Cirrhosis of the liver has been believed to be progressive and incurable. However, interferon therapy for HCV-positive chronic hepatitis and/or liver cirrhosis shows dramatic recovery in some : Hardcover. Buy Extracellular Matrix and The Liver: Approach to Gene Therapy by Isao Okazaki, Yosifumi Ninomiya, Tanikawa Kyuichi, Scott I. Friedman (ISBN: ) from Amazon's Book Store. Everyday low prices and free delivery on eligible orders. The extracellular matrix occupies approximately 20% of the normal adult brain 59 and is composed of mainly unbranched polysaccharide hyaluronic acid and chondroitin sulfate proteoglycans of the lectican family, such as aggrecan, versican, brevican, and neurocan, 60 where hyaluronic acid acts as a backbone to recruit proteoglycans and.

The hepatic extracellular matrix (ECM) is a complex network of macromolecules that not only provides cells with an extracellular scaffold but also plays an important role in the regulation of cellular activities. In normal liver, the ECM comprises less than 3% of the relative area on a tissue section and approximately % of the wet weight. Summary Describing state-of-the-art research techniques for clinicians and introducing important clinical perspectives for basic scientists, this reference examines some significant areas of investigation into the biology of the extracellular matrix and its implications in human pathophysiology.;Focusing on the liver and providing a broad survey of the latest information . Machine derived contents note: Table of contents for Extracellular matrix and the liver: approach to gene therapy / edited by Isao Okazaki [et al.]. --Bibliographic record and links to related information available from the Library of Congress catalog --Information from electronic data provided by the publisher. May be incomplete or contain. Divided into six sections, this book addresses the basic science of the extracellular matrix and discusses the strategies for the treatment of cirrhosis of the liver, with a .

Describing state-of-the-art research techniques for clinicians and introducing important clinical perspectives for basic scientists, this reference examines some significant areas of investigation into the biology of the extracellular matrix and its implications in human pathophysiology.;Focusing on the liver and providing a broad survey of the latest information available, Extracellular Price: $ The fact that reorganization can be separated to some extent from growth in the regenerating liver implies that a unique set of signals controls the restructuring process. One likely candidate for this role is the hepatic extracellular by: 4. Abstract. The extracellular matrix is a complex network of macromolecules that interact with one another as well as with cells in tissues. It comprises both interstitial stroma and the basement membrane that surround the epithelial tissues, nerves, fat cells and by: 1. sion. An additional influence of the extracellular matrix on morphogenesis and cellular metabolism can be ascribed to the storage and release of growth factors which is modulated by their binding to specific matrix components [1,2]. The most abundant proteins in the extracellular matrix are members of the collagen family. Colla-.